We’re on a mission…

We’re on a mission…

Clinical Trials

Q-Metrx provides quality controlled services for electrophysiological data collection, quantitative analysis, data management, statistical analysis, and publication of findings.

Electroencephalography Capabilities

With the aid of the pharmaco-EEG, essential information can be obtained in early drug development regarding CNS penetration and efficacy of new substances as follows:

  • Evidence for substance penetration (bioavailability) in the CNS on the basis of PD changes. In addition to the classic PK parameters (e.g., tmax, Cmax, AUC and t½), EEG/ERP parameters can be used to demonstrate time- and dose-effect correlations.
  • Proof of CNS effects of a substance by comparison of quantitative EEG (qEEG/ERP) changes between pre- and post-dose measurements.
  • Characterization of psychotropic properties of a substance by comparison with psychotropic class effects of marketed drugs. Classic psychotropic drugs show typical pharmaco-EEG profiles, thus allowing assignment of new substances in many cases.
  • Determination of new substance’s therapeutic window. The dose at which a new substance can be statistically distinguished from placebo, and at which it displays a psychotropic effect in comparison with a reference preparation, is often a therapeutically effective dose.
  • Proof of adverse CNS effects of non-psychotropic substances (e.g., sedation produced by anti-hypertensive drugs or anti-histamines, changed convulsion threshold due to antibiotics).
  • Determination of the bioequivalence of two different galenic dosage forms by quantitative comparison of CNS changes.
Q-Metrx has Experience with
  • Healthy Normal Volunteers

As well as people suffering from:

  • Schizophrenia
  • Alzheimer’s
  • Major Depressive Disorder
  • Essential Tremor
  • Narcolepsy
  • Sleep Apnea
  • Insomnia
  • Periodic Limb Movement Syndrome/Disorder (PLMS/D)
  • Restless Legs Syndrome (RLS)

Q-Metrx has clinical trial experience with drugs and medical devices for the treatment of various conditions.

Education and Training

EEG and qEEG Course is now available ON-DEMAND. Learn at home at your own pace. Continuing education credit available.
Video Education

Our Location

new_officeOur office is located at

1577 E. Chevy Chase Drive
Suite 340
Glendale, CA 91206
(818) 637-8200